Baltimore is the most populous city in the U.S. state of Maryland, the fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a estimated population of 595,218 in 2023. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today it is the most populous independent city in the nation. As of 2023, the population of the Baltimore metropolitan area was estimated to be 2,921,051, making it the nation's 20th largest metropolitan area. Baltimore is located about 40 miles (64 km) north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2023 estimated population of 10,042,122.

